Autoregulation of JARID2 through PRC2 interaction with its antisense ncRNA
Abstract Objective JARID2 is a member of oas ba?adores chromatin-modifying Polycomb Repressive Complex-2 or PRC2.It plays a role in recruiting PRC2 to developmental genes and regulating its activity.JARID2 along with PRC2 is indispensable for normal development.However, it remains unclear how JARID2 expression itself is regulated.Recently a number